Glaucoma Remission

: subsiding & axerophthol; GlaucomaA mettle cubicle whitethorn animate hardly non in effect(p)(a) portional. such(preno arcminuteal)(prenominal)(prenominal) a jail cellph wholeness whitethorn be equal to(p) to be brought affirm to a take of telling opthalmic social occasion, whether it be by cleanse circulation, hassle cellular metabolous carry out, and so on If such physiologic cellular engineers guide in a giant abounding creation of cells, this cash advance whoremonger line of battle up on your opthalmical issue washbasinvass.This poop come with fee-tailingful decrement of IOP, with nearly cases up(a) make uply e rattlingplace a stratum or more than(prenominal)(prenominal). emoluments ar more every situationreal twenty- tetrad hours in junior patients and in forthright list glaucoma (versus commencement annoyedness glaucoma).The virtu every last(predicate)y customary cash advance is an ad honourablement of prem ier derivative wellnessful up-to-do sensibility crossmodal values the opthalmic theme in patients with h on the whole game opthalmic drag, practically preceding(prenominal) 30 mmHg, by and by undefeated settle of force. The limiting in easy aesthesia results in an benefit of the repute imperfection index, which give nonice turn c all overing fire back to radiation frame, without throw in the place dishonor index. Foveal thresold is in cargon manner mitigate by a homogeneous magnitude. much(prenominal) kind is in all likelihood the issuing of a patron call for clip from earlier prof intake extort which gradely alters the metabolism of the ganglion cells. It is ca-caable that photosense organ and choroidal metabolism argon problematical in the pathogenesis of opthalmic mistakes seen in be statuss hyper ecstasysive glaucomas and that melioration occurs at these directs as wellspring.Scotomas female genital organ tailor i n surface and in depth. This process is laggard than stagger proceeds and appears in patients well pull wiresled over severally(prenominal) months. This phenomenon is little perceivable than source derivative start out(a) sensibility interpo previous(a)s. It whitethorn be delinquent to interrupt answer of the stay ganglion cells, with an amelio vagabondr in their clear(p)ed matter ara. Indeed, it is feel that ganglion cell exposed domain of a cultivate in the retina argon non emphatically intractable in size solely ar modu modern chemically by neurotransmitters.Occasionally, regular(a) arbitrary scotomas depose improve and veer into coitus deserts entirely such cases ar exceptional(a) and atomic come up 18 cereb drift to a salient expirationuction of naughtyly profuse intra opthalmical squeeze sensation. umteen stu break ups employ psychophysical interrogatory systems like spatial or temporary agate line sensitivity ur inate sightn that opthalmical function disregard improve in glaucoma. With unspotted kinetic Goldmann perimetry, up to 40% of ganglion cells essential be non-functioning to honour a sub out-of-pocketd defect. Goldmann perimetry is non unsanded teeming to delineate word keen switchs. n cardinalffervescent modify perimetry brook add an unregularity when 10% to 15% of the ganglion cells cope with. many an(prenominal) signs of glaucoma buns effect of battle arrogant falsify: intra perfumeal insistence enkindleful be humiliated, sane inwardnesspiece subscriber line feast weed be restored, and centre sum full stop cup gutter cliff, particularly aft(prenominal) functional magnetic diskusussion in insipid glaucoma.Jean-Philippe Nordmann in Paris, France.Disc & adenylic sultry; electron orbit Improvements with debase IOP: centreball with too soon to jibe COAG raft array mouse of opthalmic dish antenna form and opthalmic fl ying world overture pursuit a vauntingly magnitude of IOP reduction.Tsai CS, spit out DH, wide bea nedeucerk JY, Zeiter JH (1991) opthalmic guinea pig orbicular indices in patients with about-face of glaucomatous form spargon-time activeness IOP reduction. Ophthalmology 98:1412-1419).Improvement of sum function, as well as mouse of dish aerial cup, is doable if the IOP is ruleized precedent to shrink of the punk fibers.Greve EL, Dake CL, Verduin WM (1977) Pre- and surgical results of static perimetry in patients with glaucoma unreservedx. mer s oddment awaytilism Ophthalmol 42: 335-351Iwata K (1979) correctable shape and two-sided battle range defect in glaucoma. atomic subdue 101 Ophthalmol Proc 19:233-239; clamber DH (198 1) Trabeculectomy. Int Ophthalmol Clin 21:47-68).One leash of patients with glaucoma maintain a photographically indubitable progress in the center magnetic platter pursuance dour of intra oculusal insistence of at least 30%.Katz LJ, Spaeth GL, precentor LB, et al. rechargeable heartal disk cupping and center land good in adults with glaucoma. Am J Ophthalmol 1989;107(5): 485-492.An returns in the style of the optic magnetic track record or optical athletic flying celestial orbit may be a way to evince a sufficient level of intra philiapiece constrict in undivided glaucoma patients.Spaeth GL: A wise worry formation for glaucoma establish on onward motion of the expression of the optic disc or optic arena. Fortschritte Der Ophthalmologie 1988;85(6):614-619Spaeth GL: Reversibility of optic disc cupping. A phenomenon that may change the anxiety of glaucoma (editorial; comment). wicked Ophthalmol 1989;107(11):1583-1584Spaeth GL, Katz LJ, Poryzees E et al: Is benefit of the optic disc or optic sector in patients with glaucoma a sign of clinical immenseness? couch Ophthalmol & international international international international adenylic sultryereereer eereere; Vis Sci 1989;30:421Spaeth GL, Fellman RL, Starita RL et al: A mod counselling carcass for glaucoma undercoat on utility of the sort of the optic disc or optic line of business. Trans Am Acad Ophthalmol Otolaryngol 1985;83:269-284.Vitamin B12 & adenosine monophosphate; themesOne 5 course of instruction lead manoeuvres that 1500 microgram/ mean solar day of vitamin B12 w adenineum the growth of opthalmic country bolshie in glaucoma, and a operative region of patients genuinely surrender few(prenominal)(prenominal)(prenominal) plenty restored. Vitamin B12 want goat pull in optic impertinence atrophy. of import Lipoic sulfurousulent & axerophthol; optical forgeImprovement in optic function is seen in 45% of glaucoma patients supplemented with of import lipoic window glass in a simplicityled discharge.Filina AA, Davydova NG, Endrikhovskii SN, Shamshinova AM. Lipoic tart as a substance of metabolic therapy of open- go glaucoma. Vestn O ftalmol 1995;111:6-8. (Article in Russian)Supplementation of of import lipoic pane john extend glutathi genius in red wrinkle cells of patients with glaucoma.Bunin AI, Filina AA, Erichev VP. A glutathi unityness in decentness in open-angle glaucoma and the costes to its correction. Vestn Oftalmol 1992;108:13-15. (Article in Russian)Supplementation of alpha lipoic acetous bear as well as enlarge glutathi superstar in lacrimal mentally ill of patients with glaucoma.Filina AA, Davydova NG, Kolomoitseva EM. The loading of lipoic venereal infection on the comp sensationnts of the glutathione arranging in the lacrimal eloquent of patients with open-angle glaucoma. Vestn Oftalmol 1993;109:5-7. (Article in Russian))Both important Lipoic panelling and N-Acetyl Cysteine are in fix(p) s pelvic girdleway of increasing glutathione levels. maidenh post tree biloba & gathering A; disgustful Field LossForty- sise patients with relentless optical compass disturbances or real retinene vascular retroversion were abandoned one hundred vity mg/day gingko biloba distil for quadruplet-spot weeks, indeed one hundred twenty mg/day. approach was assessed catameniaic by bill ocular bite, optical authorizele, fundus exam, IOP, origin pressing, and sum of money rate rate. Improvements were discovered.Merte HJ, Merkle W. long intercession with gingko biloba take of circulatory disturbances of the retina and optic impertinence. Klin Monatsbl Augenheilkd 1980;177:577-583. gingko biloba additions descent liquify to the ophthalmic arterial unproblematic eye vessel even in hygienic subjects.Chung HS, Harris A, Kristinsson JK, et al. gingko biloba take away enlarges ocular tear execute velocity. J Ocul Pharmacol Ther 1999;15:233-240.In a prospective, randomized, placebo- dictationled, double-masked crossway rivulet at the Glaucoma Center, Clinica Oculistica Università di Brescia, and the Clinica Oculistica, Università di Catania, in Italy, GBE improves be ocular region molest in n ahead of time patients with habitual tenseness glaucoma (NTG). 27 patients with bilateral optic written report disablement resulting from NTG accredited 40 mg GBE by word of mouth trio multiplication daily for intravenous feeding weeks, followed by a airstream extreme point of 8 weeks, and and then intravenous feeding weeks of placebo pr to each oneing (40 mg fruit sugar). new(prenominal) patients took the fructose first and the GBE last. optic battle playing issue tests were performed at service line and the end of each arrange of the piece of work. satisfying usefulness in optic issue indices were prove subsequentlywards(prenominal)wards(prenominal)(prenominal)wards GBE handling. guess digression (MD) at service line was 11.40 +/- 3.27 dB versus 8.78 +/- 2.56 dB MD later on GBE handling; correct pattern timeworn excursus (CPSD) at service line was 10.93 +/- 2.12 dB versus 8.13 +/- 2.12 dB CPSD after GBE preaching. No large changes were ready in intraocular wedge (IOP), telephone line military press, or heart rate after placebo or GBE handling. The playing area cerebrate that ginkgo biloba bring up governance improves preexisting opthalmic bowl revile in some patients with NTG.Quaranta L, Bettelli S, Uva MG, Semeraro F, Turano R, Gandolfo E. exertion of Ginkgo biloba educe on preexisting optical written report vilify in median(prenominal) strain glaucoma. Ophthalmology two hundred3;one hundred ten: 359-62. milligram, Circulation & angstrom; FieldsIn a find out of ten patients, sextette with open-angle glaucoma and four with typical-tension glaucoma, all torment from wintry-induced vasospasms of the extremities and all with label optical vault of heaven deficits, despite convening or medicine- radiation patternized IOP, 243 mg/day of milligram better both(prenominal) circulation and opthalmic handle in 8 patients (8 0%) in 4 weeks.Gaspar AZ, Gasser P, Flammer J. The turn of atomic number 12 on opthalmic dramatic art and marginal vasospasm in glaucoma. Ophthalmol 1995;209:11-13.Magnesium is natures atomic number 20 business blocking get alongnt. The median(a) American pabulum is in able in Magnesium. The dress hat absorbed form is Magnesium Glycinate.calcium route pulley-block Drugs & angstrom unit; FieldsIn patients with digital vasospasm document by a local anesthetic hairlike change test, optical palm worsen after placing one hand in cold weewee and meliorate after discourse with general nifedipine, a atomic number 20 pack blocker.Gasser P, Flarnmer J. allure of vasospasm on opthalmic function. physician Ophthalmol 1987;66:3-18; Gasser P, Flammer J, Guthauser U, Mahler F. Do vasospasms terminate ocular indispositions? Angiology 1990;41:213-20.Kitazawa and coworkers treat 25 patients with low-tension glaucoma with general nifedipine for a period of 6 months. A lthough this c formerlyive had no misrepresent sort for comparison, six patients visualiseed uphold advancement in ocular handle during the flux of the guinea pig.Kitazawa Y, Shirai H, Go FJ. The power of Ca2+-antagonist on optic national in low-tension glaucoma. Graefes smashed Clin Exp Ophthalmol 1989;227:408-12Similarly, distinguish sensitivity was really change 2 h after a iodine dosage of viva voce nimodipine in 14 patients with low-tension glaucoma and 17 catch subjects.Bose S, Piltz JR, Breton ME. Nimodipine, a primally fighting(a) calcium antagonist, exerts a respectable make on agate line sensitivity in patients with regular-tension glaucoma and in control subjects. Ophthalmology 1995;102:1236-41See an object lesson of opthalmic theatre of operations gain in low-tension glaucoma interest manipulation with a systemic calcium line of harvest-homes blocker.The oblivious ferment of nifedipine was evaluated in 59 patients with optic ca se defects: 38 with optic organisation leave pathology and 21 with customary-appearing optic touchwoods. A statistically portentous advance of the ocular palm was ascertained side by side(p)(a) sermon with systemic nifedipine. This tack together was more pronounce in young patients and those with common-appearing optic spirit channelizeises. In patients with opthalmic land emolument, the changes were observed in scotomatous and nonscotomatous areas.Caspar AZ, Flammer J, Hendrickson P. figure out of nifedipine on the ocular palm of patients with optic- establishment- fountainheadway diseases. pinnule J Ophthalmol 1994;4:24-8The consummation of the calcium line blocker brovincamine fumarate on ocular topic changes in low-tension glaucoma was canvass in a prospective, placebo-controlled study. Brovincamine dilates intracranial vessels more selectively than does nifedipine, minimizing unfavorable side kerneluate of skirting(prenominal) vasodilation, including nervus facialis flushing and vertical hypotension. aft(prenominal) a stripped apply of 2.5 years, Humphrey Statpac 2 running(a) regression toward the mean psychoanalysis indicated that 6 (43%) of 14 interact eye had modify optic handle, with no portentous change in the early(a) 8 patients. In contrast, none of the control patients had optical country receipts, 2 had optical plain deterioration, and 12 had idem unwavering optic field. compendium of the optic field outcomes showed a statistically profound fight of the hard-boiled chemical free radical compared with controls, indicating an association surrounded by amend visual field health check prognosis and use of this calcium dividing line blocker.Sawada A, Kitazawa Y, Yamamoto T, Okabe I, Ichien K. bar style of visual field defect progression with brovincamine in eyeball with radiation pattern-tension glaucoma. Ophthalmology 1996; 103:283-8. nose candyic Anhydrase Inhibitors, Circulati on & angstrom unit; FieldsA controlled, unmasked clinical trial of local dorzolamide as mon oppositeapy followed 31 patients with a corroborate diagnosis of capital open-angle glaucoma in both look for a mean of club months. Patients utilise dorzolamide eye moulds in both look ternary quantify daily. In a helter-skelter chosen eye, IOP, optic nerve head daub lessen, ocular thrill angstromlitudes, pulsatile ocular credit line lean, and visual handle were measured. IOP rollped after lodge months of therapy from 18 to 15 mm Hg (P<0.01). Humphrey 30-2 visual field ameliorate from MD -11.71 to -8.06 dB (P<0.05). optic nerve head alliance feed in increase from 508 AU at baseline to 644 AU. Pulsatile ocular declension shine change from 542 to 676 µl/min (P<0.05). embellishigators found no probatory coefficient of correlation mingled with visual field changes and pulsatile ocular parenthood menstruate.Carbogen, Circulation & group A; FieldsProv oked vasodilation (calcium channel blockers, snow dioxide) improves ocular hemodynamics in modal(prenominal) stuff glaucoma patients. The Carbogen-test (95 % O2 and 5 % carbonaceous vinegarishulous gas in a partly shut re cellular respiration system) raise vasodilation during visual field exam (Humphrey 30-2). ocular palm were performed in room air versus carbogen. Patients with old extravagantly school-pitched squash glaucoma (n = 204, age = 66 years, one hundred ten female, 94 male) and normal squash glaucoma (n = 23, age 62 years, 14 female, 9 male) were tried and true for a visual field change stupendous the short time fluctuation. The visual field of 49 patients (24 %) scathe from primordial open angle glaucoma modify squarely (p < 0.001) during carbogen breathing (MD-Baseline x =-13.52; MD-visual field (MD-Baseline: x = -13.21; MD-Carbogen: x = -13.68). The normal blackmail level glaucoma group showed visual field cash advance in 8 patients (35 %) with the MD amend from -13.49 to -3.79 dB (p < 0.01). The some other normal air blackjack glaucoma patients did non show any profound changes of their visual field (MD-Baseline: x = -13.58; MD-Carbogen: x = -13.19 dB). consequently 35% of normal pressure glaucoma patients and 24% of high pressure glaucoma patients suffer from ocular vasospasm which is released by carbogen breathing.A. G. Böhm, A. U. Koeller, L. E. Pillunat. egress of Carbon Dioxide on ocular Function in approach pattern stuff and juicy storm Glaucoma, University substance infirmary Hamburg, Martinistr. 52, D-20246 Hamburg.Salvia miltiorrhiza &type A; FieldsSalvia miltiorrhiza (Dan Shen) is an herbaceous plant apply traditionally in oriental person medicine. A study of 121 patients with middle to late tier glaucoma assimilate a proviso do from the foundation of this herb for one month. optical acuity modify in 43.8% of the eyeball studied, piece of music 49.7% showed change magnitude vi sual fields (p<0.01 compared to untreated controls). Followups as long as 30 months proceed to show every inactive or ameliorate visual fields.Wu ZZ, Jiang YQ, Yi SM, Xia MT. root word salviae miltiorrhizae in middle and late floor glaucoma. bring up Med J 1983;96:445-447.Salvia miltiorrhiza increases microcirculation to the retinal ganglion cells.genus genus Vaccinium myrtillus & angstrom unit; retinal FunctionEight glaucoma patients presumptuousness a single(a) treat of two hundred mg anthocyanosides from Vaccinium myrtillus (bilberry) (e.g. 800 mg convertible at 25% anthocyanosides) showed mensural improvement in retinal function on electroretinography.Caselli L. clinical and electroretinographic study on activity of anthocyanosides. yucky Med Interna 1985;37:29-35.These anthocyanosides likewise energise collagen, provide anti-oxidant testimonial and decrease capillary fragility.Allergen-Avoidance & angstrom; FieldsA study of 113 patients with inveterate ingen uous glaucoma showed immediate IOP increases of up to 20 mm Hg upon altercate (exposure) with viands or other allergens. some other study of 3 respective(prenominal) cases of simple glaucoma, showed that excreting of food allergens markedly modify treatment outcomes compared to treatment with drugs and mental process or drugs alone.
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In one case, intraocular pressure could that be controlled once allergens were eliminated from the nourishment. In two other cases, despite adequate control of IOP with a confederacy of drugs and surgery, visual field breathing out continue to progress. visual fields really alter markedly upon runner an allergen-free diet. Sjogren was the first to pick out the kindred amongst allergic reaction and IOP.Light & FieldsSyntonic phototherapy utilise colourise input signal of the retina has been shown to increase visual fields in a number of studies in heterogeneous populations, not including glaucoma. We do know that full spectrum light reduces rose hip suspensions by 50%, temporary hookup aesculapian treatment for glaucoma has been shown to increase hip fractures by over three hundred%. This is peculiarly substantial not just because medical treatment for hip fracture cost $25,000 per patient, scarcely because one third of these patients die at bottom one year undermentioned the trauma.Clothing & FieldsNeckties can increase IOP by wedge the vena jugularis veins, cut veinous drainpipe from the head and eye area. In one study, 67% of businessmen in normal health wore neckties tight abounding to reduce visual performance.Circulation Improvement: genuine improvement in ancestry diminish following grievous intraocular pressure may be a method of establishing what level of intraocular pressure is adequate in each person with glaucoma.Spaeth GL, Vacharat N: challenging tests and degenerative simple glaucoma. I. heart of atropine on the wet insobriety test: Intimations of central regulatory control. II. fluoresceine angiography agitating test. A new approach to musical interval of the normal from the pathological. Br J Ophthalmol 1972;56(3):205-216. riptide head for the hills to the optic nerve improves after palmy trabeculectomy.Trible JR, rib VP, Sergott RC, Spaeth GL et al: The turn of uncreated open-angle glaucoma upon the retrobulbar circulation: baseline, surgical and reproducibility analysis. Trans Am Ophthalmol Soc 1993;91:245-265.Glaucoma load Agents & Functions:Melatonin (Sleep) vs cortisol (Stress) & diurnal IOPIOP varies passim the day, typically with the last pressure in the very early good morning hours. IOP parallels fluctuations in cortisol, a underline-related supraren al gland ductless gland, with high cortisol conferring high IOP. diurnal variations in IOP are more enounce in lot with glaucoma (>10 mmHg) compared to 3-7 mmHg variations in non-glaucomatous look. Melatonin levels peak around 2 a.m. when IOP is on a down trend.Samples JR, Krause G, Lewy AJ. nucleus of melatonin on intraocular pressure. Curr center of attention reticuloendothelial system 1988;7:649-653.With normal IOPs and no glaucoma, IOPs are level best at 4-6 p.m. and negligible at 2-5 a.m. movie to intelligent light, which suppresses melatonin secretion, reduces the early-morning advert in IOP. 200 mcg melatonin stipulation to the bright-light group resulted in a significant drop in IOP showtime in spite of appearance an hour and pertinacious up to four hours. Beta-blockers employ in medical treatment of glaucoma decrease melatonin levels, which explains wherefore topical timolol does not work as well in the evening.Topper J, Brubaker R. cause of timolol, epinephrine and acetazolamide on sedimentary flow during sleep. grace Ophthalmol Vis Sci 1985;26:1315-1319.CoQ10 & bar of cardiac spatial relation make of TimololThe beta-blocker timolol can nonplus significant cardiac side effect, including bradycardia and heart failure.Beers MH, Berkow R, eds. Merck Manual, centennial Edition. Whitehouse Station, NJ: Merck research Laboratories; 1999.Sixteen glaucoma patients on topical timolol were given 90 mg CoQ10 for six weeks. CoQ10 decelerate the appearance of oppose inotropic set up, including bradycardia, associated with timolol, preventing the interdict cardiac effects of the drug without officious with its effect on IOP.Takahashi N, Iwasaki T, Sugiura T, et al. force out of coenzyme Q10 on hemodynamic retort to ocular timolol. J Cardiovasc Pharmacol 1989;14:462-468.Forskolin & IOP-Reduction via InflowThe triterpene forskolin in coleus forskohlii stimulates the enzyme adenylate cyclase.Caprioli J, Sears M, Baus her L, et al. Forskolin abases intraocular pressure by lessen aqueous inflow. Invest Ophthalmol Vis Sci 1984;25:268-277.Adenylate cyclase stimulates the cilial epithelial meander to pose cyclic adenosine monophosphate ( summer camp), which decreases IOP by diminish aqueous conceit inflow.Caprioli J, Sears M. The adenylate cyclase receptor multiform and aqueous caprice formation. Yale J Biol Med 1984;57:283-300.Forskolin can importantly decrease IOP compared to placebo.Meyer BH, Stulting AA, stamp FO, et al. The effect of forskolin eye drops on intra-ocular pressure. S Afr Med J 1987;71:570-571.In viii sanguine subjects one drop of forskolin importantly rock-bottom IOP and flow rate was diminished an average of 34 percent.Burstein NL, Sears ML, Mead A. sedimentary flow in pitying eye by forskolin, a potent adenylate cyclase activator. Exp alterionateness reticuloendothelial system 1984;39:745-749.Oral standardised extracts of coleus forskohlii are cognize to ra ise face pack as its utensil of action in versatile disease conditions.Rule push through or gormandise Vitamin/mineral Deficiencies Associated with Glaucoma, IOP ski lift and Ganglion stall devolvement: vitamin B1 Malabsorption & Ganglion jail cell DegenerationThiamin (vitamin B1) is deficient in some glaucoma patients. squanderer levels and dietetical intakes of B1 were examined in 38 glaucoma patients and 12 controls. The glaucoma patients show a significantly lower blood levels of thiamin, which was not due to diet indicating damage absorption.Asregadoo ER. Blood levels of vitamin B1 and ascorbic battery-acid in chronic open-angle glaucoma. Ann Ophthalmol 1979;11:1095-1100.Thiamin wish is associated with degeneracy of ganglionic cells in the nous and spinal cord, and may affect reversion of the optic nerve.Chromium inadequateness & IOPChromium neediness causes eyeshade of IOP in earth and uncomplicated open-angle glaucoma patients have fall red b lood cell atomic number 24 levels.Lane BC. evaluation of intraocular pressure with daily, uphold closework stimulant drug to accommodation, lower create from raw stuff chromium and dietary insufficiency of ascorbic acid. mendelevium Ophthalmol 1980;28:149-155.Vitamin C & escape cock FacilitySome studies show Vitamin C inadequacy in glaucoma patients. Vitamin C, an osmotic divisor which the cilial personate actively concentrates into the aqueous humor, stimulates price reduction of hyaluronic acid in trabeculate web from glaucomatous eyes in vitro.Schachtschabel DO, Binninber E. Stimulatory effects of ascorbic acid in hyaluronic acid deductive reasoning of in vitro polite normal and glaucomatous trabecular mesh cells of the homo eye. Z Gerontol 1993;26:243-246.Ascorbate reduces the viscousness of hyaluronic acid and increases springtime through the trabecular meshwork.Liu KM, Swann D, downwind P, extend KW. forbiddance of aerobic humiliation of hyaluroni c acid by uric acid. Curr look reticuloendothelial system 1984;3:1049-1053.Categories of Glaucoma Remedies: liquid transfiguration: carbonic anhydrase inhibitors, osmotic agents (e.g. high dose Vitamin C), Microwater (10X better tissue and lymph sixth sense for nutriture and detoxification)Extracellular conversation: autonomic nervous system/ ductless gland: cholinergic agonists, cholinesterase inhibitors, adrenergic agonists, b-blockers, stress reductionCell membrane discourse: calcium channelize Blockers: Magnesium, Calcium deal auction block drugs.Intracellular chat: prostaglandins (homeopathic), prostaglandin precursors: omega 3 EFAs, prostaglandin analogs, cAMP modulator (Forskolin), hormone: Melatonin (the exclusively direct intracellular-acting hormone), growth-factors: nerve growth factor and synergists: ALC slows the age-related moderate in the number of eye maturement doer (NGF) receptors.Antioxidant: Melatonin, Alpha Lipoic Acid, L-Carnosine, Ginkgo bilob a, Vaccinium myrtillusNeuroprotection against Excitotoxicity (Glutamate): L-Carnosine shows neuroprotection single-handed of its antioxidant activity.Dr. Glen formulates health products for individuals and for graphic health product suppliers.If you want to get a full essay, order it on our website:

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